Uniform protein labeling in intact tissues is a challenge. An approach that allows antibodies to seep within organs could ...

YUMAB’s antibody discovery and development ... but great effort is being channeled into targeting more complex and difficult antigens, such as multimembrane-spanning receptors, receptor ...

Determining how to predict the antibody-antigen interactions was the biggest challenge. The researchers focused on the ...

Bispecific antibodies (bispecifics) can simultaneously target two distinct antigens or epitopes ... makes bispecifics effective in treating complex diseases, including certain cancers, autoimmune ...

Repetitive HIV vaccinations can lead the body to produce antibodies targeting the immune complexes already bound to the virus ...

Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby ...

The researchers observed variability in the cellular recycling process depending on the IgG1 clone and the targeted antigen. “[This] was perhaps not super surprising, but often people tend to have a ...

For some HIV vaccines, repetitive immunizations lead to a chain reaction of antibody production against immune complexes ...

"These anti-immune complex antibodies have not been studied in ... some of the antibodies were not binding directly to the HIV viral antigen, but to immune molecules on its surface.