The variable region confers an antibody's antigen-binding specificity. This region contains two fragment antigen binding (Fab) domains, each capable of binding a specific epitope (the part of an ...

YUMAB uses libraries of close to germline origin, but highly diverse antigen ... whole antibody-discovery process in vitro and bypassing animal immunization, YUMAB eliminates potential epitope ...

and epitope-optimized antibody–drug conjugates, to bispecific antibodies and chimeric antigen receptors for cell-based therapies. RubrYc’s collaboration model includes options for co-discovery ...

Determining how to predict the antibody-antigen interactions was the biggest ... it could produce 3D structures for more than ...

Recombinant Monoclonal Antibodies: It is made up of identical antibody chains that target the same epitope of a certain antigen. Recombinant Multiclonal Antibodies: They are a mix of carefully ...

The antibody 7E11 binds to the intracellular epitope ... Grimm J (2011) Targeting the internal epitope of prostate-specific membrane antigen with 89 Zr-7E11. J Nuclear Med 52(10):1608-15.