and epitope-optimized antibody–drug conjugates, to bispecific antibodies and chimeric antigen receptors for cell-based therapies. RubrYc’s collaboration model includes options for co-discovery ...
Malaria remains a significant global health challenge, causing over 600,000 deaths annually despite existing prevention and treatment measures. Current vaccines and monoclonal antibodies (mAbs) ...
Bispecific antibodies (bispecifics) can simultaneously target two distinct antigens or epitopes, offering novel therapeutic strategies such as enhancing immune cell targeting of cancer cells or ...
This work is published in Science in the paper, “Protective antibodies target cryptic epitope unmasked by cleavage ... with recombinant PfCSP. Using our antigen-agnostic workflow, we identified ...
A technique invented by the lab, known as Electron Microscopy-Based Polyclonal Epitope Mapping ... some of the antibodies were not binding directly to the HIV viral antigen, but to immune ...