Sequence of the gene CCR5 Delta 32 in acrylic paint on polyester taffeta. The CCR5 gene produces the CCR5 receptor protein which normally inserts into the cell membrane. The human immunodeficiency ...

These sites bind to coreceptor CCR5 or CXCR4 on the membrane of the host cell (center panel), an event that initiates steps that culminate in the fusion of the HIV envelope with the host cell ...

Here, we investigated the relative contributions of the CCL2/CCR2 versus CCL5/CCR5 chemokine axes in OA pathogenesis. Results Mice lacking CCL2 or CCR2, but not CCL5 or CCR5, were protected against OA ...

This should be highlighted as a critical next step for validating the efficacy of CCR5 antagonists. The studies accessed limited cognitive outcomes (only one reported a cognitive outcome). Given the ...

The chemokine receptors CCR5 and CXCR4 are the two major coreceptors for HIV entry. Numerous efforts have been made to develop a new class of anti-HIV agents that target these coreceptors as an ...