When the fork stalls due to an obstacle on the DNA (Figure 1), the cell activates the replication checkpoint to send a signal to arrest the progression of the cell cycle. Another example of ...

While the multiciliation cycle followed the transcriptional phases of the traditional cell cycle, DNA replication did not occur and the cells did not end up dividing. Instead, they grew a bunch of ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

A team has unearthed new findings about what happens during the minutes and hours after a cell divides, expanding our understanding of human biology -- and potentially leading to better medicines.

The precision of this process depends in large measure upon stringent regulatory mechanisms that couple DNA replication to cell cycle progression. Initiation must be triggered at the appropriate time ...

We also discovered that this breakage mechanism only occurs at the beginning of the cell cycle phase, when DNA replication ...

Replication of DNA DNA replication is the process by which a cell makes an identical copy of its DNA. Gene expression Only a fraction of the genes possessed by any particular cell will be expressed.

“If you impose a structure on it, which is this replication-driven cell cycle structure, then suddenly it goes from ... and some regions of the DNA are more tightly packaged than others, so this form ...

Nagayama, K. and Hirooka, Y. (2025) Changes in the Mechanical Environment of the Nucleus with Cell Crowding and Its Effects on DNA Damage Resistance. Journal of Biosciences and Medicines, 13, 230-242.

TAg expression and viral replication occurred after the first round of host DNA replication, and TAg expression also depended on the cell's going through a first round of replication. If Needham ...

The following is a summary of “Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma,” published in the January 2025 issue of Urology by Chen et al. Clear cell ...