This approach enhanced cytotoxic T cell activation, inhibited tumor growth, and worked synergistically with immunotherapy in a mouse model of melanoma.

Cytotoxic T cells are an important component of the ... molecular mechanism that leads to the faster and stronger activation of cells with nuclear invaginations: "Their special cellular ...

Immunostimulant therapy using agonistic cytokines or activating antibodies has been associated with off-target side effects, failure to preferentially activate cytotoxic lymphocytes (CTLs) over ...

Cellular immunity is a protective immune process that involves the activation of phagocytes, antigen-sensitized cytotoxic T cells and the release of cytokines and chemokines in response to antigen.

One particular challenge in the treatment of cancer is therapy resistance. An international research team has now discovered ...

The antibody has shown promising results in preclinical studies, demonstrating 'superior' anti-tumour activity.

Microbiotica, a clinical-stage biopharma company, has presented new data on MB097 at the AACR IO meeting held in Los Angeles.