Indeed, HCV has been identified as one of the globally ... designs to mimic specific regions of the viral glycoproteins E1 and E2, known as neutralization epitopes. These were transferred onto ...

Indeed, HCV has been identified as one of the globally ... designs to mimic specific regions of the viral glycoproteins E1 and E2, known as neutralization epitopes. These were transferred onto ...

studies in chimpanzees showed no protection. † Signal sequence of E1 and E2 proteins replaced by the signal sequence of HSV 1 plycoprotein D.

[17] Eight donor mice were immunized with a HCV vaccine containing pVAX-HCV Core, E1 and E2 DNA (100 μg); Core, E1 and E2 protein (25 μg) in PBS solution and montanide (50 μl) ISA-51 (Seppic Inc., ...