During the endosome–lysosome transition, the compartmental pH drops, which is conducive to the function of lysosomal acid hydrolases. Damaged lysosomes are eliminated by lysophagy, yet the ...
The Lysosomal Metabolomics and pH Core’s overarching goal is to understand the mechanistic link between lysosomal activity and aging in Alzheimer’s Disease. To accomplish this, the core will support ...
A recent study published in eLife has uncovered a crucial mechanism in cellular material management: endosome maturation ... late endosomes and eventually to lysosomes, where they are fully ...
Endocytosis and degradation of the membrane receptors in the lysosome controls the activation of intracellular ... US show that hepatocyte growth factor regulates endosome membrane invagination and ...
De Duve named these new organelles "lysosomes" to reflect their lytic nature. That same year, Alex Novikoff from the University of Vermont visited de Duve´s laboratory. An experienced ...
Every time a shuttle docks with the International Space Station (ISS), a delicate dance unfolds between the shuttle's docking ...
(6) Lysosomes directly take up mitochondria by the lysosomal membrane invagination. (7) Endosome/pre-lysosome directly ‘hit and run’ with mitochondria or MDV to form mitochondria-lysosome ...
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