Small-molecule enzyme-inhibitors often display insufficient affinity and selectivity for their targets causing unwanted side effects when used as drugs. Molecularly imprinted polymers prepared ...

11) and our understanding of ACE made a compelling argument for a new attempt at designing small molecular weight inhibitors. We had at our disposal not only an enzyme assay but also a highly ...

Microglia, the brain’s immune cells, play vital roles in clearing toxins and maintaining neuronal health but can also ...

According to the DFTQC, it tested vegetables being sold through the Kalimati Fruits and Vegetables Market on Tuesday midnight for chemical contamination. Sanjeev Kumar Karn, director general of the ...

Angiotensin converting enzyme inhibitors and angiotensin receptor blockers are commonly used to treat hypertension and/or a range of progressive end-organ diseases. The success of each of these ...

Keloids are fibrotic scars that extend beyond the boundaries of the original wound, often causing physical disfigurement and ...

A recent study by a team from Chiba University has demonstrated a promising approach for fighting antibiotic resistance by identifying a compound, V-161, that inhibits a sodium-pumping enzyme critical ...

A collision happens. Someone is hurt, a head injury, a concussion. Just as the first responders arrive to help the person, ...

Influencing their activity can control their rates of reaction. Different chemicals can influence enzyme activity. Inhibitors can be used to stop an enzyme from binding to its substrate.

ACE inhibition is a sufficiently well accepted treatment modality, and most of the guidelines addressing treatment of hypertension, renal disease, and/or cardiovascular disease have this ...

The study's findings are crucial in the rapidly emerging field of developing disease-modifying therapies that target microglia.