The epigenetic state of chromatin, gene activity, and chromosomal positions are interrelated. A research team from the IPK Leibniz Institute (IPK) and the Karlsruhe Institute of Technology (KIT) ...
In recent years, biomedical laboratory research has undergone tremendous change, to the extent that computers have frequently replaced test tubes. In this context, many discoveries now start with ...
To do so, they developed a transgenic mouse model carrying a slime mold endonuclease that ... the team observed that DNA breaks and subsequent repair lead to the erosion of the epigenetic landscape.