The epigenetic memory of a cell defines the set of modifications to the cell's deoxyribonucleic acid (DNA) that do not alter the DNA sequence, and have been inherited from the cell from which it ...
A new example of the power of bioinformatics is presented in the study published in the journal Leukaemia part of the Nature group ... The study makes epigenetic maps of over 200 cell lines ...
Chromosomal rearrangements, such as chromosome segment inversions, may affect the epigenetic landscape as well as gene expression. Different kinds of chromosome segment inversions have been found ...
the team observed that DNA breaks and subsequent repair lead to the erosion of the epigenetic landscape. This means that while, normally, cells have genomic regions with high levels of histones bound ...