Importantly, these DNA breaks induced in the system—dubbed “ICE,” for Inducible Changes to the Epigenome—do not lead to changes in DNA mutation rates, thus ruling out the possibility that any observed ...

In recent years, biomedical laboratory research has undergone tremendous change, to the extent that computers have frequently replaced test tubes. In this context, many discoveries now start with ...

Chromosomal rearrangements, such as chromosome segment inversions, may affect the epigenetic landscape as well as gene expression. Different kinds of chromosome segment inversions have been found ...