Structure of an epithelial cell, with its apical side at the top and its basolateral sides on the bottom and sides. Far right ...

the epithelial layer of the crypt ... in detail, the goblet cell nucleus is colored in dark blue and the apical portion, expanded with mucin-secreting granules, which extends into the intestinal ...

2 Additionally, they employ organoids to investigate development, drug response and toxicity, and interactions between epithelial cells and host microbiota or pathogens. Traditional methods produce ...

Intestinal organoids that are classically grown in 3-D matrices are cystic, which means that they have a monolayer of epithelial cells with fluid inside. The cells interact with the matrix on the ...