Physiological extracellular matrix (ECM) calcification or mineralization is restricted to bones, teeth and the hypertrophic zone of growth plate cartilage. In contrast, pathological ECM ...
1 According to popular medical textbooks, cartilage is made up of only one type of specialized cell called a chondrocyte, which is small and secretes large quantities of extracellular matrix, giving ...
Regenerative medicine is a field of science that aims to heal or replace damaged cells, tissues, and organs for patients who suffer injuries or degenerative disorders. It encompasses tissue ...
Osteoarthritis disproportionally affects postmenopausal women, and a biological mechanism for why this occurs has been largely unkown, hindering development of effective treatments. That is in part ...
In severe cases, cartilage wears so thin that joints ... Once inside the body, these nanofibers mimic the extracellular matrix of surrounding tissue, matching its structure, motion, and bioactive ...
Most cartilage relies on an external extracellular matrix for strength, but "lipocartilage," which is found in the ears, nose and throat of mammals, is uniquely packed with fat-filled cells called ...
In the future, a person’s own cells could be used in a 3D printer to make bioprinted cartilage to help repair damaged joints. Brian Eames is a scientist and professor ...