In accordance with our hypothesis of induction of IDO and recruitment of Tregs, a case study of a glioblastoma patient has described the development of a strong CMV-specific T cell response ...

They are elevated in blood of glioblastoma patients and within this tumor's tissue itself. Indoleamine 2,3-dioxygenase, IDO, converts tryptophan to kynurenine. IDO activity enhances Treg formation ...