Because the authors do not find a loss in virus binding this allows them to hypothesize that the glycan content presents a barrier for the stable membrane-membrane contact between virus and cell. They ...

Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme's ligand-binding site, interfering with recognition and binding to the glycosylation proteins' normal glycoprotein ...

Glycans function as structural components in the plant cell wall, assist in the folding of nascent proteins, act as signaling molecules in stress and plant defense responses, and serve within the ...

The glycan-targeted antiviral action of PRM-A ... interrupting viral transmission focused on lectins, carbohydrate-binding proteins that are derived from plants or bacteria, which showed strong ...

TABLE 1. Binding specificity of Siglecs toward N-glycans observed in this study. Recombinant Siglec-Fc chimera proteins were used in this study. This work was supported by the National Institutes of ...

There are increasing numbers of reports of bacterial glycosylation in pathogenic ... physical methods Lectins (carbohydrate-binding proteins) have been used as tools for glycoprofiling, most ...

Glycans are fundamental biological sequences that are as crucial as DNA, RNA, and proteins. As complex carbohydrates forming branched structures, glycans are ubiquitous yet often overlooked in ...

these N-glycans were found to modulate binding avidity of ACPA to citrullinated antigens. Conclusions The vast majority of ACPA-IgG harbour N-glycans in their variable domains. As N-linked ...

His work builds on the identification of the immunoregulatory functions of galectins, an evolutionarily-conserved family of endogenous glycan-binding proteins. Among his most prominent findings, ...