Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme's ligand-binding site, interfering with recognition and binding to the glycosylation proteins' normal glycoprotein ...
The ability to alter proteins to refine control over binding affinity and specificity can create tailored therapeutics with reduced side effects, highly sensitive diagnostic tools, efficient ...
The glycan-targeted antiviral action of PRM-A ... interrupting viral transmission focused on lectins, carbohydrate-binding proteins that are derived from plants or bacteria, which showed strong ...
There are increasing numbers of reports of bacterial glycosylation in pathogenic ... physical methods Lectins (carbohydrate-binding proteins) have been used as tools for glycoprofiling, most ...