A MASH-inducing diet caused DNA damage in the liver cells (hepatocytes) of MUP-uPA mice. This triggered the DNA-damage response (DDR; a signalling pathway that repairs DNA damage and limits the ...

Cellular senescence, where cells permanently stop dividing, plays a complex role in liver health. In a recent review article, ...

as cell membrane stabilisers and permeability regulators that prevent hepatotoxic agents from entering hepatocytes; (iii) as promoters of ribosomal RNAsynthesis, stimulating liver regeneration ...

An international team of researchers has taken an important step toward understanding how gene expression is controlled ...