Signal transduction describes the process of conversion of external signals, such as hormones, growth factors, neurotransmitters, and cytokines, to a specific internal cellular response ...

DIRECT EFFECTS: Steven Hebert, left, and Edward Brown and colleagues found that Ca 2+ receptors influence signal transduction. "Although the importance of intracellular Ca2+ ions in signal ...

T. Fernandes-Alnemri, R.C. Armstrong, J. Krees, S.M. Srinivasula, L. Wang, F. Bullrich, L.C. Fritz, J.A. Trapani, K.J. Tomaselli, G. Litwack, E.S. Alnemri, "In vitro ...

as well as signal transduction-targeted therapeutics in the form of biological agents and small molecular drugs used to treat human diseases such as cancer, autoimmune disorders, and others.

You will be redirected to our submission process. G protein coupled-receptors (GPCRs) or seven-transmembrane receptors (7TMRs) are the most prevailing class of signaling transduction molecules in ...

The purine/purinergic system has emerged as a fundamental regulator of cellular communication, influencing various physiological processes such as metabolism, energy balance, and signal transduction.

Researchers from the University of Illinois have discovered a key factor responsible for facilitating signal transduction in Cys-loop receptors, providing insight into a longstanding question in ...

The main goal of our laboratory is the identification and characterization of signal transduction pathways that cause the dysregulation of growth and inhibition of apoptosis that characterize advanced ...

We have long utilized human cells rather than cell lines in order to address the parameters, signal transduction and pharmacological aspects underlying clinically relevant basophil and mast cell ...