Immune checkpoint blockade is one of the major advances in cancer treatment in recent years. However, the majority of immune checkpoints are embedded in the cell membrane and this fact represents a ...
Immunotherapy, particularly immune checkpoint blockade, has revolutionized cancer treatment. By targeting proteins like PD-1 and CTLA-4, these therapies unleash the immune system’s natural ...
PDUFA action date of July 22, 2025, with priority reviewWOBURN, Mass., Jan. 21, 2025 (GLOBE NEWSWIRE) -- Replimune Group, Inc. (NASDAQ: REPL), a clinical stage biotechnology company pioneering the ...
and mechanisms of immune regulation. A strength of the program is the ability to translate laboratory findings into effective clinical applications. Scientists from our program have played a central ...
If these preclinical results can be translated to clinical applications, it could pave the way for improved responses to immune checkpoint blockade therapies, particularly for challenging “cold ...