We offer a comprehensive suite of immune checkpoint-related products, including high-quality proteins, inhibitor screening ...

The FDA has accepted a BLA for treatment with RP1 in combination with Opdivo for patients with advanced melanoma who have ...

Immunotherapy, particularly immune checkpoint blockade, has revolutionized cancer treatment. By targeting proteins like PD-1 and CTLA-4, these therapies unleash the immune system’s natural ...

Immune checkpoint blockade is one of the major advances in cancer treatment in recent years. However, the majority of immune checkpoints are embedded in the cell membrane and this fact represents a ...

Georgia Tech researchers have developed biosensors with advanced sleuthing skills and the technology may revolutionize cancer ...

“We hope our research will enable clinicians to make important decisions over which patients would be better served by surgery or immune checkpoint blockade by immunotherapy.” Dr Amanda Kirane, ...

An international team of UK and US scientists has discovered that the activity of macrophages—a type of white blood cell that ...

The advent of immunotherapy based on immune checkpoint inhibitors has improved the treatment of advanced hepatocellular carcinoma and is now the first-line standard of care for systemic therapy.1 In ...

A new research paper was published in Oncotarget's Volume 16 on January 20, 2025, titled "Anti-correlation of KLRG1 and PD-1 expression in human tumor CD8 T cells." ...