In obesity and insulin resistance ... mechanism of PKC activation is through ligand binding to G-protein-coupled receptors, which for example occurs during α-adrenergic stimulation.
Insulin receptors are widely expressed and distributed across the brain and are mainly the insulin receptor-A isoform rather ...
Understanding the molecular mechanisms of insulin resistance remains a major medical challenge of the twenty-first century. Over the last half-century, many hypotheses have been proposed to ...
In a recent study published in the journal NPJ Metabolic Health and Disease, researchers hypothesize that the degradation of endogenously secreted insulin (as opposed to the commonly believed ...
Type 1 Diabetes Cells have the normal number of insulin receptors on their surface. They respond to the presence of insulin Type 2 Diabetes Cells have a decreased number of insulin receptors on ...
A study on GLP1RA medications found that behavioral side effects likely do not result from direct action on GLP1R.
Semaglutide combined with automated insulin delivery enhances glucose control in type 1 diabetes, lowering insulin ...
Glucagon-like peptide 1 receptor agonists (GLP1RA)—medications for type 2 diabetes and obesity that have recently been making headlines due to a rise in popularity as weight loss agents—have been ...