In obesity and insulin resistance ... mechanism of PKC activation is through ligand binding to G-protein-coupled receptors, which for example occurs during α-adrenergic stimulation.
Understanding the molecular mechanisms of insulin resistance remains a major medical challenge of the twenty-first century. Over the last half-century, many hypotheses have been proposed to ...
Type 1 Diabetes Cells have the normal number of insulin receptors on their surface. They respond to the presence of insulin Type 2 Diabetes Cells have a decreased number of insulin receptors on ...
In a recent study published in the journal NPJ Metabolic Health and Disease, researchers hypothesize that the degradation of endogenously secreted insulin (as opposed to the commonly believed ...