Does MYC binding to chromatin serve transcription-independent functions, including the regulation of chromosomal integrity, gene expression, chromatin structure, cellular replication and genomic ...

However, the study published Aug. 28 in Nature Communications identifies the MYC gene as a common denominator across prostate cancers. The work demonstrates that initial MYC activation attracts ...

Researchers have long known that there is a relationship between the cancer-associated gene MYC (pronounced "Mick") and exercise adaptation. When human muscles are exercised, MYC is found to ...

Expression of the cell cycle inhibitor p15 INK4b is suppressed by the Myc oncoprotein and induced by transforming growth factor-β (TGF-β). The transcription factor Miz-1 activates the Ink4b ...

Scientists at MedUni Vienna, led by Lukas Kenner, have made a groundbreaking discovery that could change how we understand and treat prostate cancer. Their research, published in the journal Molecular ...

M. Conacci-Sorrell et al., “Myc-nick: a cytoplasmic cleavage product of Myc that promotes α-tubulin acetylation and cell differentiation,” Cell, 142:480-93, 2010. Free F1000 Evaluation When Maralice ...

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, ...