We previously showed that this cartilage-targeting IGF-1 fusion protein (CV1574-1) promoted growth plate function in a GH-deficient (lit) mouse model. Here, we studied CV1574-1 in a second mouse model ...

Background Until now, there was no effective cure for cartilage injury and degeneration commonly occurring in joint injury and OA. The efficiency of cartilage regeneration in young people is generally ...

Decalcified wax section through the top of the head of a mouse thigh bone (femur). This tissue section was stained with haematoxylin and eosin (H&E). Cartilage (round purple cells and dark purple ...

Cartilage-forming cells are extracted from the knee, processed in a lab and implanted in the damaged area to help with cartilage repair. The study is comparing this treatment to microfracture surgery, ...

Currently, the standard procedure is microfracture surgery, which involves creating small fractures in the bone to stimulate new cartilage growth. With further development, researchers believe ...

Surgical approaches to the treatment of focal cartilage defects can be classified into repair, replacement, and regeneration therapies. Marrow stimulation procedures such as microfracture result in a ...

While evidence has supported these changes, it does not appear that we have seen the same reduction in marrow stimulation technologies such as microfracture as one might expect.” “Similarly, many ...

Osteochondral autograft transfer – Plugs of cartilage are taken from the non-weight-bearing areas of the knee and transferred to the damaged areas of the joint. Microfracture – Tiny holes are made in ...