Oral absorption of naltrexone is rapid with peak plasma concentrations occurring after three hours and remains metabolically active for 24–72 hours, however, the precise pharmacodynamics are not ...

Naltrexone is administered in much higher ... Griffith scientists were the first to identify a common trigger or cell ...

The pathophysiology of cholestatic itch is complex and no single treatment has proved definitive. Naltrexone is an opioid receptor antagonist, which reduces central opioidergic tone, believed to be ...

Naltrexone is relatively well tolerated ... Acamprosate modulates glutamate neurotransmitter pathways through an unknown mechanism to reduce alcohol withdrawal hyperexcitability.

Naltrexone is an FDA approved drug (for alcoholism ... However, considering the extent of use in other conditions, and uncertainty about the mechanism of action study is needed in a diverse set of ...