Messenger RNA abundance is determined by balancing transcription and RNA decay. mRNA stability can be rapidly modulated to alter the expression of specific genes thereby providing flexibility in ...

The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But where does translation take place within a cell?

Messenger RNA carries genetic information from DNA in the highly protected nucleus out to the rest of the cell, where structures called ribosomes can build proteins according to the DNA blueprint.

The platform’s scalability, rapid production and relatively straightforward manufacturing process mean that mRNA therapeutics are a powerful alternative to traditional small molecule drugs and DNA ...

InDevR partners with Aldevron to describe how the VaxArray 5′CapQ assay can be used to measure intact mRNA in a single assay to streamline bioprocess development.

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

Learn about our Editorial Policies. “During the pandemic, obviously because of the accelerated speed, a lot of those processes were just inherited from traditional manufacturer workflows,” explained ...

We found that inclusion or exclusion of the 3′UTR of an mRNA that encodes a transcription factor did not change how much of the transcription ... showing it makes a big difference where in that ...

Researchers at Tel Aviv University have achieved a breakthrough in drug delivery: they have successfully transported lipid nanoparticles encapsulating messenger RNA (mRNA) to the immune system of ...

C2H2 zinc finger proteins are the largest group of DNA-binding factors for transcription—the process of copying genetic ...

This approach quantifies mRNA transcription and degradation rates ... Use of single-cell RNA sequencing to track genes in zebrafish In the study, researchers used a technique called single-cell ...

Using a novel, RNA-based approach, we sought to restore this ... We used lipid nanoparticles to deliver mRNA and siRNA to human PCa cells to evaluate our technique's ability to both restore ...