In 2013, Jason McLellan and his colleagues determined the molecular structure of RSV's F glycoprotein in the prefusion conformation (the shape it takes before the virus infects a cell).

RSV F proteins sit on the viral surface ... syncytial virus matrix protein lattice and its coordination with fusion glycoprotein trimers, Nature Communications (2024). DOI: 10.1038/s41467-024 ...

This is the RSV fusion glycoprotein is shown (left) in its pre-fusion state in complex with an antibody (red and white ribbon) and (right) in its post-fusion shape. Disclaimer: AAAS and EurekAlert!

Similar to respiratory syncytial virus (RSV), immunizing mice with pre-fusion F protein elicits higher ... Stable trimeric pre-fusion F protein Post-fusion F protein Glycoprotein G These antigens have ...

New Delhi: The Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) has ...

The vaccine comprises an mRNA sequence that encodes the RSV F glycoprotein, which is essential for the virus' ability to infect host cells. The drug also received US Food and Drug Administration ...