Our objective is the elucidation of signalling pathways with an impact ... modulating gene function to promote cholesterol efflux from peripheral tissues (reverse cholesterol transport) via ...
"We found that we are activating the reverse cholesterol transport pathway, which lowers cholesterol," Thayumanavan elaborates. He further theorizes, "We believe that activation of fat oxidation ...
The endogenous pathway involves the liver synthesizing lipoproteins. TG and cholesterol ester are generated by the liver and packaged into VLDL particles and then released into the circulation.
Get Instant Summarized Text (Gist) Beneficial gut microbes and the body collaborate to regulate fat metabolism and cholesterol levels. An enzyme in intestinal cells converts bile acids into bile ...
Conclusion Our study uncovers a novel functional crosstalk between aberrant lipogenesis and cholesterol biosynthesis pathways in hepatocarcinogenesis, whose concomitant inhibition might represent a ...