T-cell therapy, originally developed for haematological malignancies, has recently emerged as a promising therapy for ...

T cells, move over. B cells are now reported ... The answer may lie, in part, in the innate mechanisms of antigen binding by professional APCs. DCs and macrophages express a variety of lectins ...

Despite advances in conventional treatment modalities, patients with metastatic CRC often face limited options and poor outcomes. Chimeric antigen receptor-T (CAR-T) cell therapy, initially successful ...

The study, published today in the journal Nature Immunology, focused on chimeric antigen receptor (CAR)-T cells, an effective therapy against cancer, especially leukemia and lymphoma. T cells ...

CAR-T cells that had past contact with antigens behave differently than those that have never encountered an antigen. "Unlike most drugs, CAR-T cell products are not uniform. We know that ...