A tumor comprising many cells can be compared to a natural population with many individuals. The amount of genetic diversity reflects how it has evolved and can influence its future evolution. We ...

Remodel the surrounding tumor stroma by protease secretion to escape into adjacent blood vessels. Support collective and independent migration to distal locations where they can form new tumors. The ...

Researchers have discovered how a particular protein affects the growth and spread of colon cancer in humans. The study not ...

These terminal sugar residues on glycoproteins and glycolipids modulate key cellular processes such as immune evasion, cell adhesion, and migration. Aberrant sialylation is driven by overexpression of ...

The Under-oil Open Microfluidic System enhances tumor cell-ECM interaction studies, improving anti-metastatic drug testing ...

Results: RAGE upon activation by its ligands enhances downstream signaling pathways, contributing to breast cancer cells migration, growth, angiogenesis, metastasis, and drug resistance. In addition, ...

Functional experiments confirmed that recombinant human TWEAK (rhTWEAK) promoted tumor migration and invasion, while Fn14 antagonist impaired the metastasis-promoting function of rhTWEAK (IDDF2023-ABS ...

a journal of the American Association for Cancer Research. Normally, MICAL2 plays an important role in cell migration and morphology. But when the researchers measured gene expression in PDAC ...