Dysfunctional endothelium displays activation of vascular NADPH oxidase, uncoupling of endothelial nitric oxide synthase, increased expression of endothelin 1, a changed balance between the ...

The three cell types that Khalil's approach generated were endothelial cells (the vascular cells that form the lining of blood vessels) and smooth muscle cells and pericytes (perivascular cells ...

In a groundbreaking study led by Dr. Ying Chen and her team from Ruijin Hospital, Shanghai Jiao Tong University School of ...

Atherosclerosis involves multiple processes including endothelial dysfunction, inflammation, vascular proliferation and matrix alteration. Vascular proliferation contributes to the pathobiology of ...

The team detected a protein frequently found in senescent cells on the surface on the vascular endothelium, or inner lining of blood vessels, in the human body. They also discovered that elderly ...