Whole-cell patch recordings. These recordings were obtained from pyramidal neurons in artificial cerebrospinal ... phosphonovaleric acid (AP5). Current-clamp experiments to measure firing rates ...

Specifically, he studied synaptic mechanisms in motor neurons ... giant cells from strange creatures, such as squids and snails, to more physically representative cells,” remarked Neher. The next set ...

I am interested in understanding how small groups of neurons in the central nervous system function together. At the cellular level, we study the ionic currents that influence a neuron's intrinsic ...

“This whole-cell patch method is really the gold standard for looking at synaptic and other events ... that allowed scientists to record from specific neurons in a living ...

The technique, called whole-cell patch-clamp electrophysiology, measures changes in two types of neurons—pyramidal and GABAergic—as well as changes in how signaling molecules, called ...

Research by the team of Prof. Joris de Wit (VIB-KU Leuven) and colleagues highlights the differences between two types of these brain cells—intratelencephalic (IT) neurons and pyramidal tract ...