Both types of change in Wnt signalling have been linked to cancer. Therefore, a great deal of effort is being invested worldwide in developing therapeutic agents that function by fine-tuning the ...

This lab looks at the role that Wnt plays in the early transformation of a cancer into a metastasis. Also trying to understand the role of pancreaticogenic diabetes in the pathogenesis of pancreatic ...

Aberrant Wnt signaling has also been identified as a key mechanism in cancer biology. This article summarizes both the canonical (β-catenin dependent) and non-canonical (β-catenin independent) ...

Elucidating Signaling Pathways that Maintain the Niche for Stem-Like Cells in Cancer We believe that uncovering pathways controlling of stem ... In particular, our laboratory will focus on the niche ...

In this infographic, we take a closer look at the relationship between cell signaling and cancer, highlight what happens when signaling goes wrong and explore how critical mediators of abnormal ...

I was able to be one of the first people to use both in cancer research. Through this experience I also met some great collaborators who helped advance my research. While I was at MIT, I studied a ...

Dewpoint Therapeutics’ second development candidate, DPTX3496 is an oral, small molecule acting via a novel ...

Cancer metastasis—the spread of cancer to ... microenvironment engage in increasingly dynamic communication through WNT signaling, a process driven by the transcription factor SP1." ...

Allarity Therapeutics, Inc. ("Allarity” or the "Company”) (NASDAQ: ALLR), a Phase 2 clinical-stage pharmaceutical company ...