Farnesyl diphosphate synthase (FPPS) is a key enzyme in this pathway, and its inhibitors have garnered significant attention for their potential therapeutic applications, particularly in cancer ...
Its pipeline includes Tipifarnib, which is a Farnesyl transferase inhibitor for HRAS Mutant Solid Tumors, Chronic Myelomonocytic Leukemia, KO-947, which is an ERK inhibitor for MAPK Pathway Tumors ...
Despite the minimal clinical efficacy seen with farnesyl transferase inhibition in previous pediatric clinical trials, the farnesyltransferase inhibitor (FTI) tipifarnib has now demonstrated ...
In a report released today, Roger Song from Jefferies maintained a Buy rating on Kura Oncology (KURA – Research Report), with a price target of ...
an orally bioavailable farnesyl transferase inhibitor combination with alpelisib for patients with PIK3CA-dependent HNSCC; and KO-2806, a farnesyl transferase inhibitor for the treatment of solid ...
Its pipeline includes Tipifarnib which is a Farnesyl transferase inhibitor for HRAS Mutant Solid Tumors, Chronic Myelomonocytic Leukemia; KO-947 which is an ERK inhibitor for MAPK Pathway Tumors ...
an orally bioavailable farnesyl transferase inhibitor combination with alpelisib for patients with PIK3CA-dependent HNSCC; and KO-2806, a farnesyl transferase inhibitor for the treatment of solid ...