Lung cancer treatment and outcomes are profoundly influenced by the tumor microenvironment (TME), particularly in resectable ...

While these organoids are derived from cancer cell lines and don’t accurately recapitulate the complexity of the tumor microenvironment, the team plans to test their approach using patient-derived ...

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...

Interestingly, these processes are all sensitive to the concentration of oxygen present in the microenvironment. Rapidly proliferating cells cause the NSCLC tumor to extend beyond the oxygen ...

D tumoroid models transform cancer research, accurately reflecting tumor biology and enabling effective drug testing and ...

Tongue cancer (TC) cells can enter a chemo-resistant state by activating pathways related to autophagy and cholesterol synthesis, report researchers. Using a large-scale library of TC organoids ...

Dr. Won Jin Ho presented a talk as part of the Immunology Neighborhood Seminar on “Overcoming the tumor immune ...

Cancer remains one of the most complex diseases ... dissociation and enzymatic digestion for generating patient-derived organoids (PDOs), emphasizing the importance of maintaining the tumor ...

Brain Tumor Organoids Accurately Model Patient Response to CAR T Cell Therapy Dec. 9, 2024 — Researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM ...

Tongue cancer organoids mimic patient-specific tumor biology Autophagy and cholesterol biosynthesis aid chemo-resistance New drug targets could enhance treatment outcomes Tongue cancer (TC ...