Here they find that glycan content (measured using the PNA lectin) of the overexpressed protein and total molecular weight, that includes amino acid weight and the glycan weight, is negatively ...

It can be applied to imaging other glycosylated RNAs using aptamers for other glycans. FUT10 and FUT11, originally annotated as α1,3-fucosyltransferases, are actually protein O ...

A new bridge built as part of a project to widen a section of the A1 has been found to have defects. The Allerdene Bridge, in Gateshead, was replaced by a new structure that opened in September ...

A seven-month-old baby has died after a crash on the A1 as officers investigate whether the incident was linked to icy conditions. The baby boy suffered serious injuries when the vehicle left the ...

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China University of Chinese Academy of Sciences, Beijing 100049, China ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Automated glycan assembly (AGA) streamlines the synthesis of complex oligosaccharides.

“Palleon’s glycan editing therapeutic has the potential to significantly improve treatment outcomes in patients who have autoimmune diseases including lupus nephritis, with a therapy that ...

On the N-terminal, each Siglec has a V-set immunoglobulin (Ig) domain that recognizes sialic acid–containing glycans (Duan and Paulson, 2020). There are 15 human Siglecs and 9 murine Siglecs. Among ...