The tide has largely turned against alcohol. Drinking, at least in moderation, was once seen as a harmless—or even healthy—indulgence that could strengthen your heart and even lengthen your ...

Graca et al. reports a fundamental missing link in the ethanol metabolism of mycobacteria and illuminates the role of a flavoprotein dehydrogenase that acts as an electron shuttle between an uncommon ...

Jan. 23, 2025 — Researchers have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some ...

Single-molecule biophysics is the study of the dynamics and interactions of individual biomolecules to understand how they carry out their functions in living cells. For example, monitoring the ...

Correspondence to Dr Ailsa Hart, IBD Unit, St Mark's Hospital and Imperial College London, Watford Road, London HA13UJ, UK; ailsa.hart{at}nhs.net Over the last 10–15 years, our understanding of the ...

The work presents a molecule detection method for single-molecule localization microscopy. By means of probabilistic thresholding with control over false positive detections, the method improves ...