These findings in the human are at the basis of our proposed structure-function model in which the antigen binding features of the germline template antibody are dictated by the somatically ...

Scientists at The University of Texas at Austin, in collaboration with researchers from the University of North Carolina at ...

Here, we discuss strategies to select the best therapeutic antigen targets, to optimize the structure of IgG antibodies and to design related or new structures with additional functions.

New research led by scientists at La Jolla Institute for Immunology (LJI) reveals the workings of a human antibody called mAb 3A6, which may prove to be an important component for Ebola virus ...

A new antibody discovery platform can delve deeper into the mechanisms underlying the processes behind Alzheimer’s and ...

A research team led by a Duke professor recently developed a novel computational model to predict antibody structures, a significant breakthrough for disease prevention efforts. A study published ...

New research led by scientists at La Jolla Institute for Immunology (LJI) reveals the workings of a human antibody called mAb 3A6, which may prove to be an important component for Ebola virus ...

A Yale-led research team has uncovered how a naturally occurring biological mechanism found in mammals is able to prevent ...

Generate Bio uses a combination of sequence and structure-based approach towards de novo design of a variety of proteins, including antibodies with desired properties. In addition to its ...

HER2 (also known as ERBB2) is a key oncogene in breast cancer and is found in 2–4% of patients with non-small-cell lung ...