Masroor Ahmad Paddar and colleagues reveal noncanonical roles of ATG5 and membrane ATG8ylation in regulating retromer assembly and function. They identify ATG5's unique non-autophagic role and show ...

This important work identifies a non-autophagic role for ATG5 in lysosomal repair and the trafficking of the glucose transporter GLUT1 to the cell surface, mediated through the retromer complex. The ...

State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China Background: Tanshinlactone is a compound derived from the herb Salvia ...