Yellow marrow is made mostly of fat. It mainly consists of mesenchymal stem cells—multipotent cells found in the supporting tissue surrounding the bone marrow called the stroma. Mesenchymal stem cells ...
The Food and Drug Administration (FDA) has approved Ryoncil ® (remestemcel-L-rknd) for the treatment of steroid-refractory acute graft vs host disease (SR-aGvHD) in pediatric patients 2 months of age ...
Through the team's efforts, researchers and doctors now have a much clearer picture of the functions of the rarer but key cells in the bone marrow such as stromal cells, bone cells, and ...
Types of Bone Metastatic Tumors Cytokines secreted by DTCs stimulate osteoclastogenesis. DTCs also co-opt stromal and blood cells of the marrow to induce osteolysis. DTCs can activate osteomimicry ...
Myelosuppression, or bone marrow suppression, is defined as a decrease in the ability of the bone marrow to produce blood cells. This may result in a lack of red blood cells (anemia), white blood ...
However, LLPC remain a challenging therapeutic target. Here, we compare the matched bone marrow (BM) and peripheral blood (PBL) plasma cell (PC) compartments of SLE and healthy donors (HD). We show a ...