stabilizer TH-301 in models of pancreatic ductal adenocarcinoma (PDAC). It was seen that treatment with TH-301 led to significant dose-, time- and cell type-dependent decreases in viability.
Cellular senescence is a process that leads to a state of irreversible cell growth arrest induced by a variety of intrinsic and extrinsic ... described the significance of regulation of senescence and ...
Despite being mainly composed of terminally differentiated myocytes that cannot re-enter the cell cycle, the heart is not a postmitotic organ and maintains some capacity to form new parenchymal ...
The following is a summary of “Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma,” published in the January 2025 issue of Urology by Chen et al. Clear cell ...
The life cycle of IEC is determined by the time span in which cells migrate from ... recent data using gene deficient mice have challenged this concept. Moreover, an apoptosis-independent mode of ...
Vascular proliferation contributes to the pathobiology of atherosclerosis and is linked to other cellular processes such as inflammation, apoptosis ... by targeting cell cycle regulation.
the tricarboxylic acid (TCA) cycle, the respiratory chain, transport of electrons ... 2015), heme- and iron–sulfur (Fe-S) cluster biogenesis, regulating cell death, and steroid synthesis. However, ...
Thomas H. Sisson, Toby M. Maher, Iyabode O. Ajayi, Jessie E. King, Peter D.R. Higgins, Adam J. Booth, Rommel L. Sagana, Steven K. Huang, Eric S. White, Bethany B ...