EPFL researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel ...
Researchers identified a key protein as a potential therapeutic target for stopping the body's immune system from mistakenly attacking itself, offering new hope for treating autoimmune diseases and ...
Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions. Their environments—water, lipid membranes, or other condensed phases—are critical to their ...
DNA-nanoparticle motors are exactly as they sound: tiny artificial motors that use the structures of DNA and RNA to propel motion by enzymatic RNA degradation. Essentially, chemical energy is ...
Novel proteins have been designed to neutralise some of the deadliest molecules in snake venom. The proteins, which were developed with the aid of deep learning, are more stable and easily produced ...
Such aggregating proteins ‘are difficult to remove by using inhibitors’, Hjerpe says. Sygnature has therefore developed a platform called Charmed to accelerate heterobifunctional degrader discovery.
A study of rare familial genetic mutations linked to early-onset dementia supports the idea that stalled protein processing contributes to Alzheimer’s disease. Alzheimer’s disease is likely caused by ...
Department of Chemistry, Stanford University, Stanford, California 94305, United States Sarafan ChEM-H Institute, Stanford University, Stanford, California 94305, United States ...