Findings could lead to new treatments for dopamine transporter-related disorders and addiction to drugs such as cocaine, ...

The results of this effort, reported in the Journal of Neurochemistry, included novel mutations in the worm gene encoding the ...

The dopamine transporter (DAT) plays a crucial role in regulating dopamine levels in the brain by facilitating the reuptake of dopamine from the synaptic cleft back into presynaptic neurons.

E18 with maximal expression early postnatal and continuing throughout life. DAT: Dopamine transporter expressed in ventral midbrain regions including the substantia nigra and ventral tegmental area.

Cocaine disrupts the normal distribution of dopamine transporters (DAT) in the brain, which can lead to long-term changes in dopamine signaling. Studies indicate that while the recovery of DAT ...