Schroeder declares an NIAID/NIH grant paid to their institution. Chen, McCormack, and Tversky declare no conflicts of interest. Introduction: Plasmacytoid dendritic cells (pDC) are unique ...

Figure 1: γ c-dependent lymphokines are required for the peripheral survival of naïve CD4 + T cells. Figure 3: Antigen-driven proliferation of CD4 + T cells is independent of γ c-cytokines.

As a metabolic center, the liver prevents inappropriate immune responses to abundant dietary antigens within the liver that could result in liver injury. This self-preservation mechanism can however ...

10, 2025 /PRNewswire/ -- Diakonos Oncology, a clinical-stage biotechnology company leveraging proprietary dendritic ... tumor antigen profile and induces powerful memory T cell responses against ...

Despite advances in conventional treatment modalities, patients with metastatic CRC often face limited options and poor outcomes. Chimeric antigen receptor-T (CAR-T) cell therapy, initially successful ...

Lessons From Taxanes Versus Eribulin for First-Line Metastatic Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer in the EMERALD Study In this pilot study, we assessed the adoptive T-cell ...

Activation of the NFkB pathway contributes to the resistance to steroids, and its activation via TLR7 and 8 pathways, along with inhibition of plasmacytoid dendritic cell (pDC) apoptosis via TLR7 ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Components of the innate immune system, such as monocytes, macrophages, dendritic cells, granulocytes, and other immune cell types demand greater ... Innate immune responses during SARS-CoV-2 ...

The $4.9 billion acquisition of Forty Seven by Gilead is an example of the explosive excitement and investment into macrophage-directed therapies, utilizing CD47 checkpoint blockades ...

Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.