Overexpression of constitutively active EZRIN T567D is sufficient to relocalize TSC complex to the endosomes and reactivate mTORC1. Our findings identify EZRIN as a critical regulator of autophagy via ...
Scientists analyzed the lengths of regions of Neanderthal DNA in 58 ancient Eurasian genomes of early modern humans and determined that ... Dec. 12, 2024 — Few genomes have been sequenced from ...
Check out the Early Edge with the best handicappers to preview every day's biggest games. From primetime picks to off-the-radar locks, Early Edge is bringing you the best bets in a quick ...
Primary endocytic vesicles fuse with early endosomes, from where cargo is either recycled back to the plasma membrane or sorted into the endo-lysosomal pathway for degradation. Clathrin-mediated ...
Unfortunately, even when LNPs reach their target cells, the nanoparticles are typically captured by endosomes -- tiny protective sacs within the cell. If LNPs can't escape, it's like a shuttle ...
Early access has become a popular release method for developers, allowing them to release an early game build while still working on it. Early access sometimes gets met with stigma, but it has ...