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Reprogramming cells for heart repair: New method transforms ordinary fibroblasts into mature cardiomyocytes
Their method relies on combining fibroblast growth factor 4 (FGF4 ... Their results revealed key improvements: better cell structure with well-defined sarcomeres and T-tubules, enhanced electrical ...
Nature2y
Regulation of TIGR/MYOC gene expression in human trabecular meshwork cells
As reported here, the major GC-induced increase of TIGR expression in HTM cells is reduced approximately 4-fold by basic fibroblast growth factor (bFGF, 100-1000 pM), with a somewhat smaller ...