Because the authors do not find a loss in virus binding this allows them to hypothesize that the glycan content presents a barrier for the stable membrane-membrane contact between virus and cell. They ...
The ability to alter proteins to refine control over binding affinity and specificity can create tailored therapeutics with reduced side effects, highly sensitive diagnostic tools, efficient ...
these N-glycans were found to modulate binding avidity of ACPA to citrullinated antigens. Conclusions The vast majority of ACPA-IgG harbour N-glycans in their variable domains. As N-linked ...
Department of Chemistry, University of California, Davis, California 95616, United States ...
Analytical Research Center for Organic and Biological Molecules, State Key Laboratory of Drug Research, Carbohydrate-Based Drug Research Center, Shanghai Institute of Materia Medica, Chinese Academy ...
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There are increasing numbers of reports of bacterial glycosylation in pathogenic ... physical methods Lectins (carbohydrate-binding proteins) have been used as tools for glycoprofiling, most ...
A breakthrough discovery in enzyme science could revolutionize the treatment of autoimmune disorders and other diseases tied ...
Our speciality is the discovery of oligosaccharide (glycan) ligands for proteins involved in innate and acquired immunity ... We offer microarray screening analyses for carbohydrate-binding proteins ...