Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen ...

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death.

The newly reported research has uncovered one mechanism, which they found is controlled by the mitochondrial ... the MCJ protein could be a new therapeutic target to correct diseases associated ...

We aimed to delineate the presence of mitochondrial formylated peptides in ARDS and characterise the functional importance of formyl peptide receptor 1 (FPR1 ... a highly regulated and complex process ...

A novel mechanism that enables cells to maintain energy production even when their main power supply drops/fails has been ...

Program in Chemical Biology, Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, Oregon 97239, United States ...

These findings open an avenue for new strategies for mitochondrial dysfunction targeting linked to ISR alterations. Excessive mitochondrial fragmentation is associated with the pathologic ...

An enzyme that helps clear damaged mitochondria can act as a molecular switch and potentially prevent neurons from dying.

No pathogenic mutations were identified in the other four patients. CONCLUSIONS This is the first point mutation in the transfer RNA gene for phenylalanine to be associated with MELAS. The absence of ...