Exocytosis, the fusion of secretory vesicles with the plasma membrane to allow release of the contents of the vesicles into the extracellular environment, and endocytosis, the internalization of ...

In NPC1 cells, SFN induces TFEB nuclear translocation and upregulates the expression of TFEB-downstream genes, promoting lysosomal exocytosis and biogenesis. While genetic inhibition of TFEB abolishes ...

The coat protein I (COPI)-coated vesicles and the COPII-coated vesicles are involved in endoplasmic reticulum (ER)-Golgi trafficking, the clathrin-coated vesicles (CCVs) mediates endocytosis and ...